Kick them in the bollocks.
Hug them and then headbutt them.
Avoid them, try and get them 'onside' or later to consider their behaviour, but if confrontation is unavoidable and all else has failed and it's me or them then they can have one 'go' at me... I turn the other cheek and if they go for that then I 'turn' nasty
i set traps.
Depending, either match or become stronger than their physicality or attack them psychologically by finding out their true weaknes.
It highly, highly depends on the details.
get one of those blow up sumo suits...
Carry a large stick.
Stay away from them or leave them - whichever applies.
They soon find a hulk in me. Most people dont mess with me
so if someones pickin on me i can send them your way?
Maybe what will you do for me? ;))