Talking about myself, I'd probably talk about what kind of work ethic I have ("I've always been a perfectionist, and I like to take my time and make sure everything is correct" or "I'm a really social person and I want to be in a place where I can interact and help people", etc) and strengths and weaknesses - I'd tell the truth. They're already expecting you to turn your weakness into a strength i.e "I'm a workaholic because I like to do a thorough job". You can either play the game and feed them what they want or just be honest about what your best and worst traits are and hope they find it refreshing.
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Keep it work related, they don't care about your personal life. It's kind of a trick question
Talk about experiences based on work experience or what you think you would do in any given scenario related to a job
Best of luck :)