first, buy a book or two "for dummies" and read up on it. get a business license so you can buy stuff wholesale. choose something you are passionate about and have some knowledge. design a website to sell your product. then cross-sell on ebay or some other auction website. <br />
be very self-disciplined and driven and be prepared to keep very good financial records for Uncle Sam.<br />
that's it in a nutshell. good luck.
Is that you Egoberd?!! :) And to answer your question, maybe things like making jewellery can be done from home