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Has Anyone Been Prescribed Propantheline Bromide As A Cure For Hyperhydrosis?

I have put a lot of time into researching hyperhydrosis and one of the medications recommended by the NHS (UK) is "propantheline bromide". I went to the doctors several weeks ago. The doctor i saw on this particular date highlighted that "oxybutynin" would be available to me - however he wanted to make sure there were no underlying problems and ran a few tests. They came back satisfactory. I booked a follow up appointment, over the moon with joy thinking i would be prescribed oxy. He refused, saying in 20 years of practice he had never seen this used for HH. I cried. literally. He prescribed me with "anyhdrol forte" - a 20% aluminium chloride soln which was to be applied at night. I have never felt so much pain in my life, and the effects werent all that great either!! I am back on my way to looking for a cure.

If anyone has been prescribed with Propantheline bromide or Oxhbutynin please get in touch. Or even if you havent but just want someone to share your story with, please talk to me so i can feel like im not alone.

"sui generis" is latin for unique, one of a kind - this is how HH makes me feel.
suigeneris93 suigeneris93 18-21, F 36 Responses Apr 2, 2012

Your Response


Hi guys, I have lived with the curse that is Cranial Hyperhydrosis for about 14 years now, started when I was about 15. No need to go into too much detail as I think most of us here reading this know how it prevents any kind of social life and is pretty much horrible in every way. I have found myself making excuses to avoid even my closest friends when they suggest lunch etc so rarely see them which I hate! can't eat dinner with family, can't go to the hairdressers as my face starts pouring as soon a I sit down etc etc...

Anyway, I have finally decided enough is enough, time to to do something and start talking about it rather than hiding away in a corner. I visited a dermatologist who seemed to know her stuff. I explained that I have tried many aluminum antiperspirants with no effect at all and that over the last year or so it has started becoming more general which wakes me up a lot in the nights etc. I don't mind sweaty arm pits and feet etc to be honest as annoying as they are, but when your face looks like you have just stepped out of the shower even on a cold day it is hard to hide and hugely embarrassing.

The Dermatologist prescribed me Propantheline Bromide to try given that it is the only licensed option, although she did mention unlicensed ptions that we can try if needed. I am building up to 3 times a day for 3 months. Given that I have only had one a day for three days so far I can't comment on them too much. I will say however that I walked around a few shops in town today, normally my head would have been glistening a lot of the time but I was very much dry! A good start then. I should mention that I felt very weird after the first one, quite sick and light although I am fine today. I have also been getting signs of dry mouth but I can live with that if it means gaining some kind of life back. I am very much hoping these will be the solution.

I'll be sure to keep you updated.

Add a response...

hello.i went to doc he dd not seam to have a clue .i told him if he did not give me any i would just get them online ,and he did .i dont bother him now i just buy my own

I have been on and off it for years now, and the only reason I go off it, as I am lazy or run out. The doctor prescribed it for me where I have 1 pill, 3 times a day. If I have 2 pills, I get cottonmouth that Jim Carrey from Me, Myself and Irene would be envious of! But it works, really well too!

i have been on it for about 6 years now

Hi, I'm 22 and have developed HH over the last 3 years. I get in worst on my torso, especially my back. I have consulted with doctors, some good, some bad and have just tried Propanalol. This didn't work for me and to be honest I didn't expect it to (it's only effective in reducing sweats due to anxiety), my doctor is ringing the pharmacy about Propantheline because apparantly there was an issue with the drug or something... any information on this?

I have been taking pro-banthine for 7 years. Prescribed by doctors in uk.

It is part of family of drugs called anticholinergics and side effect is to stop sweating. Only pro-banthine is licensed in uk to be prescribed for sweating. Generic name Propantheline. A specialist dermatologist can prescribe Off License anticholinergic Glycopyrrolate which is sold in USA under name Robinul. Canada name Avert.The other not so effective anticholinergic is Oxybutynin, USA name DITROPAN.
I would say making sure these drugs are taken on empty stomach without water, hour before eating makes them work best. Depending on severity of your condition depends on how many you need to take and how effective and how long they last.

Visit site to see people's comments on taking these drugs. Use A-Z or key in name. 109 comments for Robinul by HH sufferers.

Pro-banthine is also produced by Sigma in Australia and I get this on the Internet because it gives me less gastric problems than the Archimedes version produced for Europe.


Best wishes

Keith uk

Hi there I also suffer from HH. I did so for more than 9 years before it was diagnosed, I kept being told it was the menapause!!! I am on Propantheline which has changed my life. No need to explain what it was like before as you already have experienced this. Please ask your Doctor to give you the correct treatment, Propantheline is the only thing that has worked for me.

I have tried oxybutynin and the only thing it did for me was make me itch and it really used to burn when i started to sweat. I was given probanthine and I take three pills which work really well for up to 5 hours but the problem is when I take them my mouth becomes so dry I cannot really eat unless is something like soup etc..

I have been taking Propantheline Bromide for over a year now, and it's fantastic! I spent years seeing different doctors here in NZ until I was finally prescribed this by a Doctor who came from the UK. Do yourself a really big favor and book yourself in with another Doctor. I too was prescribed that horrible high strength stuff and ended up with such a rash under my arms I was off work for two days and had to use cortisone cream to relieve it....

hi i was prescribed both i find the oxy has major and horrible side affects manly constipation and dry mouth. i have just started taken propantheline after it not being avalible for over nine months, so far ive noticed a little difference, im still waiting to here if my appeal for botox has been accepted as i know this works but its so costly

Is propantheline available in the UK currently. We need it asap for our 13 year old Golden retriever to help his urine incontinence. We cannot buy it in the Netherlands. When we run out of our last 200 tablets we have no other choice but putting him to sleep.

hi .i have been using thease tabs for about 4 years now

It works for me, however I have to take it at regular intervals and on an empty stomach. For years of living with the condition, going hungry while out and about or at work was NOT an issue in comparison with the relief of dryness. What I have to do though is not eat for up to 8 hours prior (but it might be less for you) then I take three an hour before going out anywhere, and two tablets subsequently every two hours or so after. It does give me the side effects of dry mouth, blurred vision (to some extent), even sometimes heart palpitations, but i have been on it for three years now and am still alive! I am 25 and take between 7-12 tablets daily. Although this is above the recommended max dose, I haven't suffered any long term effects and my doctor stated that an overdose just exacerbates the side effects with no long term effects.

Hi all.I have facial HH, I have been on propantheline a month, I get a dry mouth 20 mins after taking the tabs, but it hasn't reduced my sweating at all. Should it work straight away? Or does it take a couple of months to kick in? I'm taking 3 tabs before I go to sleep like my doctor said. Please do let me know if I should carry on taking them. Thanks.

I don't know why your doctor suggested taking it before bedtime when the half life is like an hour and a half, so by the time you wake up the effect has gone, i.e. it stopped you sweating in your sleep which is no good.

I take it an hour before I don't want to be sweating, so maybe an hour before work and then one every couple of hours after that.

I don't see why taking your dose at night time would help at all.

I have been prescribed propantheline bromide for HH - took it for one day then had to stop because in caused a problem with my eyes and I had to have laser surgery, my eyes are ok now and I have been told I can take them again but am very uneasy about it. What would you do?

I've used oxybutynin only as needed. "going out with friends etc.".
I has reduced sweating by about 10 to 15 %. I also use a sage tea with oxybutynin which reduces sweating by about 25 to 30 %. I would more excited to try propantheline it seems to be the better of the two.

would it not be great if someone in the know out there would give us the reason to why so many people are being denied this medication .WHY IS THERE A SUPPLY PROBLEM!!??

I have been on propatheline bromide for about 4 years and it has been absolutely brilliant for me. It took a little while to get used to the dry mouth etc but it has had a really positive effect for me. I ran out in May and have been trying alternatives since but with no luck. I really hope that they start to manufacturer it again soon!

Why oh why do they stop do things when they obviously work for so many people anybody take an alternative to propantheline bromide that works x

Hi I have been on 60mg of propantheline bromide a day for about 18 months and it my wonder drug it's fab although I still get a lot of night sweats but a small price to pay if I can b normal during day but just ran in to a nightmare there is a problem with manufacturing an it's not available until jan 2013 so am trying to find an alternative at min with not much luck

You are not alone. I have hyperhydrosis and it' dictates what I wear, what I do and so and so forth. It's uncomfortable and embarrassing and has made me a nervous wreck. I am on propantheline which works to a point but they have stopped making it and so I am awaiting to see a specialist to provide an alternative like ' oxy'. Heres hoping.<br />
My kindest regards to you and know you are most definetley not alone. Sarah. X

hi i have been given propanthaline bromide 15mg tablets for excessive sweating it worked a treat the only downside was the dry eyes and the dry mouth so after eventually finding this great life changing drug the pharmacy cant get any more due to a manufacturing problem and the doc sais there is no alternative aaarrrgggg back to the embarrassed sweaty head hope you find some help with ur HH.

Mandy I no exactly wat your goin threw because it's same for me :( it only started 3 years ago wen I was 23 completley ruined my life I always have to make excuses to getting out of doin things no1 understands :( I have been doctors several times nothing waste of time I found out for myself wat I've got by lookin on the Internet I managed to find a site just last night that sell these bromide tablets are they any good? Do they actually work? And it's really strange how no1 else in my family has this condition!?

Hi I have hyperhydrosis :( carnt tell you how horrible it is it started about 3 years ago :( I'm 26 male now I carnt do anyfing like family meals shopping anything normal like that without goin rally hot & sweating luckily I work outside :-/ if u have any ideas wat I can take to cure this please tell me :-| thank you

Hi there!! You dont have to tell me how horrible it is as i can empathise with you!! Well it depends where abouts in the world you live. i live in the UK and we have a national health service which provides numerous treatments. Firstly they recommend aluminium chloride deodorants such as anhydrol forte and driclor. you can give these a go. they can be painful and give little relief. its about finding out what works for you :)

Dear unique yes i have been subscribed them but only after reading about them online for head sweating worked great (apart from dry mouth which apparently comes with the territory with these types of drugs) but like others have been told there is no more supply I urgently need an alternative.

yeh ive just got scrip for probanthaline it stopped sweats from first tab,and i cant believe im dry.more or less couldnt sleep last night as i been so used to wet bedding for some mths and had little faith anything would help but it did.i am really tired though tday and i wont be waiting for the unexpected tnite

Hi<br />
<br />
I have taken probathine for 20 years now for facial HH. Works well except for dry mouth. Just been advised that probathine has a manufacturing issue in the UK. I rang the supplier who advised that they are the only supplier in the EU. They advised to ask my chemist to ring direct to investigate alternative supply chain. I will chase for an update. Currently had to push my Dr to prescribe oxybutynin , he did want to. I am now trying this pill

Free Botox, oh how I wished it were free here in Aus! Not so....<br />
<br />
One company has a small claim through Australian Medicare, so we are finally getting somewhere in regards to people understanding this condition. However you still are around $500 out of pocket at the end of the 50 needles.<br />
<br />
Anyway I have continued success with Perspi-guard. A product which I mentioned earlier on another speel, and I have found it to be quite good. I do however apply it every night to ensure the product continues to work. It does not sting - only if you use it on freshly shaved or irritated broken skin! I must admit my armpits become a little more hairier as I tend not to shave as much, otherwise I can't use the product for a day or so. So far it is great and I am happy to pay the $40 per bottle as it seems to last a while. <br />
<br />
I have had major HH under the arms forever as long as I can remember. I am heading towards 40, so yes quite a long time. I suggest some of you HH sufferers try and get your hands on some Perspi guard. You can buy it in Aus, don't know about other countries. Just google I guess! Let me know how you go!<br />
<br />
Good luck!

Hi there, I too live in the UK and have been prescribed propantheline bromide 15mg 3 times a day for generalised hyperhydrosis(prescribed by dermatologist). I have only been on this drug a week and it has completely changed my life for the better. Sweating has completely stopped now so no more embarrassing facial sweats while talking to people, no more wet hair, no more soaking clothes, no longer need to wear dark clothes to hide it and most of all I actually have the confidence to go out more(used to avoid going out because it was so embarrassing). I probably sound silly saying this but it has given me my life back. I'm due to go back to the dermatologist on the 13th of August and he will possibly double my dose. My only side effects were a little nausea for the first couple of days and dry mouth. All I have to do is drink more water carry a pack of mints or chewing gum which I feel is nothing considering massive difference it has made to my life.<br />
<br />

Hi Mandy!

This is a real help as it seems that you have all of the same symptoms as i do!! Im really happy to find out that you have been proscribed this. My appointment is Sept 27th and I cannot wait to see what they can do for me!! To be honest, water and mints arent really a sacrifice for getting your life back! I wish you the best of luck and hopefully i will see the same results.