After years of trying to take St. John's Wort, I finally found a brand that suits me about a year ago. I think part of the reason I was successful was because I was desperate to feel better, and therefore I pushed through the initial side effects. The worst ones were intense migraines and terrible sensitivity to sunlight. I realized that if I quit because of these side effects, I would be back in the same place I started. I'm glad I did, because after about 6 weeks taking it everyday, I started to feel better. The main thing I notice is not that I am automatically happy, but instead when I feel sad, there is a reason for it. In the past I would just be moody, gloomy, depressed, self-hating, suicidal, and all for no identifiable reason. Nowadays, I ask myself why I feel bad and can usually give an answer. That in itself is a relief, because I feel less crazy. In the past year, the fog has cleared a bit, and I am starting to figure out what I want, what I can do to make myself happy, instead of wallowing in the confusing mess. I used to feel like all that was left of me was a dimly burning pilot light. And I knew I had the potential to become a blaze of passion. I'm not there yet.
I have always been frightened of pharmaceuticals. This is why I chose SJW. I think the studies that are out there show that there are less side effects and an equivalent amount of mood enhancement. It is called an SSRI, so I believe it acts in the same way.
Does anyone know how it reacts in the liver? This is something on which I can find no info.