And Some of My Favorites

“That’s good.  You’ve taken your first step into a larger world.”
    -  Obi wan Kenobi
    -  Star Wars Episode IV:  A New Hope

"The avalanche has already started.
It is too late for the pebbles to vote."
     -  Ambassador Kosh (Ver 1.0)  -- Believers --

"This town needs an enema!" 
     -  The Joker, from the movie Batman

...and some from Star Trek:

“To all mankind: May we never find space so vast, planets so cold, heart and mind so empty, that we cannot fill them with love and warmth...”
     -  Dr. Tristan Adams to Kirk and Dr. Helen Noel, a toast.
         TOS / “Dagger of the Mind”

“Someone once told me that time was a predator that stalked us all our lives.  But I rather believe time is a companion...who goes with us on the journey, reminds us to cherish every moment...because they’ll never come again.”
      -  Picard to Riker
          Generations

“I believe that even in the worst of times, we can still find moments of joy and kindness.  If you can find that kindness, hold on to it.”
     -  Taban to Meru
         DS9 / “Wrongs Darker than Death or Night”

“Captain, the most elementary and valuable statement in science...the beginning of wisdom...is: ‘I do not know.’”
     -  Data to Picard
        TNG / “Unnatural Selection”

“You know, some of our greatest advances have come from analyzing failure.”
     -  Troi to Data
        TNG / “Peak Performance”

“You can handle defeat in two ways.  You can lose confidence or you can learn from your mistakes.”
     -  Troi to Data
         TNG / “Peak Performance”

“It’s good to know how the world works.  It is not possible to be a scientist unless you believe that all the knowledge of the universe, and all the power that it bestows, is of intrinsic value to everyone.  And one must share that knowledge and allow it to be applied...and then, be willing to live with the consequences.”
     -  Jetrel to Neelix
        VGR / “Jetrel”